Searchable abstracts of presentations at key conferences in endocrinology

ea0026p74 | Endocrine tumours and neoplasia | ECE2011

In vitro effect of the somatostatin analogue BIM 23704 on cell cycle timecourse in an ovarian carcinoma cell line

de Angelis Cristina , Pivonello Claudia , Cuomo Gaia , Sardo Attilio di Spiezio , Bifulco Guiseppe , Nappi Carmine , Sabbatino Francesco , Cariati Federica , Colao Annamaria , Pivonello Rosario

Ovarian carcinoma (OC) is associated with poor prognosis and low survival rate. Eligible treatment for advanced OC is surgery followed by chemotherapy based on a combination of Platinum and Taxol, but unfortunately long-term outcome of such therapy is disappointing. Moreover, systemic administration of cytotoxic agents is usually accompanied by a series of side effects. On the basis of this evidence, more selective and tumour cell-targeted therapeutic approaches are warranted....